EBOO: The Most Advanced Systemic Ozone Therapy Available
At Peak Body and Mind, EBOO is not an add-on or a wellness trend borrowed from a spa menu. It is a precise, physician-grade intervention for one of the most under-addressed drivers of chronic anxiety, depression, and treatment resistance: systemic neuroinflammation.
We hold double certification in ozone therapy, and we have built EBOO into the core architecture of how this practice treats complex, difficult-to-resolve cases.
What EBOO Actually Is
The principle behind it is hormesis: a controlled, momentary oxidative signal that teaches your own cells to defend themselves more effectively. Rather than introducing an external antioxidant, EBOO activates your body's own antioxidant machinery, the Nrf2 pathway, which governs your master defense enzymes: superoxide dismutase, catalase, and glutathione peroxidase.
Why This Matters For Your Brain
This is often the missing piece for patients who have tried medication, tried therapy, and still feel stuck.
How EBOO Addresses It At The Source
1
Calms the inflammatory cascade.
By suppressing NF-kB signaling, EBOO targets the cytokine burden driving neuroinflammation at its root, not just its symptoms.
2
Quiets the cellular alarm system.
Deep inside your cells, the NLRP3 inflammasome acts as a molecular alarm that, once triggered, releases some of the body's most potent inflammatory signals. EBOO acts further upstream than most interventions can reach, reducing the oxidative signal that sets this alarm off in the first place.
3
Protects your serotonin supply.
By easing the inflammatory pressure that fuels the kynurenine shunt, EBOO supports the pathway your brain uses to synthesize serotonin.
4
Restores cellular energy.
Through mitochondrial activation, EBOO supports your cells' capacity to generate usable energy, addressing the fatigue and cognitive fog that so often accompany chronic inflammatory states.
5
Improves blood flow to the brain.
By activating nitric oxide signaling, EBOO supports circulation to the prefrontal cortex and hippocampus, delivering oxygen and nutrients during the most critical windows of psychiatric treatment.
6
Supports a return to calm.
While this is not its primary mechanism, patients frequently report measurable improvements in heart rate variability and autonomic balance as inflammatory burden resolves: a meaningful secondary benefit for a nervous system stuck in high alert.
Precision, Not Guesswork
EBOO is also never delivered in isolation. It is sequenced deliberately within your broader treatment plan, informed by your labs, your neurobiological presentation, and where you are in your care. For patients with confirmed, treatment-resistant inflammatory burden, especially those who have not fully responded to standard interventions, EBOO can become one of the most consequential tools available.
Who This Is For
A Modality Most Providers Cannot Offer
F.A.Q.
EBOO (extracorporeal blood oxygenation and ozonation) draws blood through a closed, sterile circuit, oxygenates and ozonates it at a controlled concentration, and returns it to the body. It is the highest-volume, highest-precision form of medical ozone therapy available today.
EBOO processes a substantially greater volume of blood than standard autohemotherapy, under a calibrated, medically supervised protocol with individualized screening. It is a physician-grade intervention, not a menu item.
EBOO targets systemic neuroinflammation, a driver of treatment-resistant anxiety and depression in many patients. By acting on pathways like NF-kB, the NLRP3 inflammasome, and the kynurenine shunt, it addresses inflammatory biology that medication and therapy alone may not reach.
Comprehensive pre-treatment screening, including genetic and enzymatic testing specific to ozone-therapy safety, is completed before any patient begins. Concentration and duration are titrated individually and monitored throughout.
Patients with objective evidence of active neuroinflammation or a complex, treatment-resistant picture where standard approaches have plateaued. EBOO is a precision escalation, not a routine first step.
No. It is sequenced within a broader treatment plan and is not a substitute for foundational psychiatric care. Your clinician determines whether it fits your case.
It is never delivered in isolation. Timing and use are guided by your labs, your neurobiological presentation, and where you are in your protocol.
A precision tool for the cases that need it most
If standard care has plateaued and active neuroinflammation may be part of your picture, EBOO begins with a complete evaluation. We will review your labs and clinical presentation and determine whether it belongs in your broader Peak protocol.
This page is educational and is not a diagnosis or a substitute for individualized medical advice. If you are in crisis, call or text 988, call 911, or go to your nearest emergency department.
